L-5-Methyltetrahydrofolate calcium

English name: CALCIUML-5-METHYLTETRAHYDROFOLATE

Chinese name: L-5-methyl tetrahydrofolate

Alias: L-5-MTHF-Ca

Molecular formula : C40H48CaN14O12

Molecular weight :956.97372

CAS NO :151533-22-1

Uses: Similar to folic acid, it is widely used as a food fortification and food supplement raw material, but L-5-MTHF-Ca has higher bioavailability and absorption rate than folic acid.

Calcium L-5-methyltetrahydrofolate (5-MTHF) is a naturally occurring salt-forming methyl derivative of folic acid. 5-MTHF is also known as levomethyl-folate, which is the most biologically active and functional of folic acid. Form, more easily absorbed than ordinary folic acid. Common folic acid must be converted to L-type methyl folate to participate in two major metabolic pathways: methylation and DNA synthesis, the only form of free folate normally present in human plasma and cells is 5-MTHF. Lack of folic acid is usually caused by vitamin deficiency, which is insufficient for absorption. During pregnancy and breastfeeding, the need for folic acid is increased during the growth of children. Under the influence of absorption or metabolic changes or drugs, the consumption of folic acid-rich foods cannot guarantee the dose provided, so it needs to be given. supplement.

Features 

Lack of folic acid reduces the ability of cells to synthesize and repair DNA. Folic acid supplementation may be a more favorable method to increase folate lowering homocysteine levels and support normal cell proliferation, vascular endothelial function, cardiovascular disease, nervous system function, especially Supplementation of 5-MTHF during pregnancy has been shown to reduce the risk of developing neural tube defects and recurrence.